RI-2
货号：
18397-50mg 基本售价：
12600.0 元 规格：
50 mg
产品信息
概述| 货号 | 18397-50mg |
| 描述 | RI-2 is a reversible inhibitor of RAD51 (IC50 = 44.2 µM), a protein that is central to the homologous recombination process initiated upon DNA double-strand breaks and is often overexpressed in a wide range of human cancer cell types.1 At 150 µM, it has been shown to inhibit DNA repair and to sensitize cancer cells to cross-linking chemotherapy in vitro.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Budke, B.,Kalin, J.H.,Pawlowski, M., et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. Journal of Medicinal Chemistry 56(1), 254-263 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 433.3 |
| 分子式 | C21H18Cl2N2O4 |
| CAS号 | 1417162-36-7 |
| 稳定性 | ≥ 2 years |
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