货号 | 16677-50mg |
描述 | Astragalosides are bioactive saponins isolated from dried roots of plants of the genus Astragalus, which is used in traditional Chinese medicine.1 Astragaloside A is known to have diverse protective effects for the cardiovascular, immune, digestive, and nervous systems.1,2 More specifically, it protects cardiomyocytes from apoptosis resulting from ischemia/reperfusion and inhibits inflammation signaled through TNF-α.3,4 Furthermore, astragaloside A stimulates angiogenesis, promotes the differentiation of neural stem cells, and increases neuroregeneration.2,5,6 |
别名 | AST-A;AS-A;Astramembrannin I; |
供应商 | Cayman |
应用文献 | |
1.Ren, S.,Zhang, H.,Mu, Y., et al. Pharmacological effects of Astragaloside IV: A literature review. J.Tradit.Chin.Med. 33(3), 413-416 (2013). 2.Si, Y.C.,Li, Q.,Xie, C.E., et al. Chinese herbs and their active ingredients for activating xue (blood) promote the proliferation and differentiation of neural stem cells and mesenchymal stem cells. Chin.Med. 9(1), 13 (2014). 3.Liu, Q.s.,Wang, H.f.,Sun, A.k., et al. A comparative study on inhibition of total astragalus saponins and astragaloside IV on TNFR1-mediated signaling pathways in arterial endothelial cells. PLoS One 9(7), 1-9 (2014). 4.Si, J.,Wang, N.,Wang, H., et al. HIF-1α signaling activation by post-ischemia treatment with astragaloside IV attenuates myocardial ischemia-reperfusion injury. PLoS One 9(9), 1-10 (2014). 5.Wang, S.G.,Xu, Y.,Chen, J.D., et al. Astragaloside IV stimulates angiogenesis and increases nitric oxide accumulation via JAK2/STAT3 and ERK1/2 pathway. Molecules 18(10), 12809-12819 (2013). 6.Zhang, X. and Chen, J. The mechanism of astragaloside IV promoting sciatic nerve regeneration. Neural Regen.Res. 8(24), 2256-2265 (2013). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 785 |
分子式 | C41H68O14 |
CAS号 | 83207-58-3 |
稳定性 | ≥ 2 years |
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