TFC 007 (50 MG)
货号：
5108/50 基本售价：
12571.6 元 规格：
50 mg
产品信息
概述| 货号 | 5108/50 |
| 别名 | N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor (IC50 = 83 nM). Inhibits PGD2 production and late phase nasal blockage in an animal model of allergic rhinitis. Exhibits negligible effects on COX-1, COX-2, 5-LOX, LTC4 synthase, TXA2 synthase and microsomal prostaglandin E2synthase. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 487.55 |
| 分子式 | C27H29N5O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Nabeet al (2011) Inhibition of hematopoietic prostaglandin D synthase improves allergic nasal blockage in guinea pigs. Prostaglandins Other Lipid Mediat. 95 27. PMID: 21601002. |
