TA 01 (50 MG)
货号：
5383/50 基本售价：
12571.6 元 规格：
50 mg
产品信息
概述| 货号 | 5383/50 |
| 别名 | 4-(2-(2,6-Difluorophenyl)-4-(fluorophenyl)-1H-imidazol-5-yl)pyridine |
性能| 供应商 | Tocris |
| 生物活性 | Induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction at 1 μM. Inhibits cardiomyocyte differentiation at 5 μM. Potently inhibits CK1ε, p38α, and CK1δ(IC50 values are 6.4, 6.7 and 6.8 nM respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 351.32 |
| 分子式 | C20H12F3N3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming |
| 参考文献 | Lacoet al (2014) Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J.Mol.Cell.Cardiol 80 56. PMID: 25528965. |
