货号 | 2893/50 |
别名 | (2S,3S)-N-(2-Methoxyphenyl)methyl-2 |
供应商 | Tocris |
生物活性 | Potent and selective non-peptide NK1 receptor antagonist. Attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 412.57 |
分子式 | C28H32N2O |
可溶性/溶解性 | Soluble to 20 mM in DMSO with gentle warming |
CAS号 | 132746-60-2 |
参考文献 | Banget al (2003) Neurokinin-1 receptor antagonists CP-96,345 and L-733,060 protect mice from cytokine-mediated liver injury. J.Pharmacol.Exp.Ther. 305 31. PMID: 12649350. Lembecket al (1992) The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of neurogenic inflammation. Br.J.Pharmacol. 105 527. PMID: 1378337. Snideret al (1991) A potent nonpeptide antagonist of the substance P (NK1) receptor. Science 251 435. PMID: 1703323. |