CAY10668
货号:
9001252-10mg 基本售价:
12544.0 元 规格:
10 mg
产品信息
概述货号 | 9001252-10mg |
描述 | Di-, tri-, and tetramethoxystilbenes potently inhibit cytochrome P450 1B1 (CYP1B1), an isoform involved in estrogen metabolism and implicated in hormone-mediated cancers.1,2 CAY10668 is a 4-hydroxylated form of 2,2’,6’-trimethoxy-trans-stilbene. The 4-methoxylated form of the same trans-stilbenoid inhibits CYP1B1 (IC50 = 1.77 nM), suggesting that this compound may also be an inhibitor of CYP1B1.1,2 |
性能供应商 | Cayman |
应用文献 |
1.Chun, Y.J.,Oh, Y.K.,Kim, B.J., et al. Potent inhibition of human cytochrome P450 1B1 by tetramethoxystilbene. Toxicology Letters 189, 84-89 (2009). 2.Chun, Y.J.,Lim, C.,Ohk, S.O., et al. trans-Stilbenoids: Potent and selective inhibitors for human cytochrome P450 1B1. Med.Chem.Commun. 2, 402-405 (2011).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 286.3 |
分子式 | C17H18O4 |
稳定性 | ≥ 2 years |
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