Cochlioquinone A
货号：
19440-2.5mg 基本售价：
12544.0 元 规格：
2.5 mg
产品信息
概述| 货号 | 19440-2.5mg |
| 描述 | Cochlioquinone A, a bioactive compound isolated from D. sacchariandBipolaris sp., is an inhibitor of diacylglycerol kinase (DGK; Ki = 3.1 µM) and diacylglycerol acyltransferase (DGAT; IC50 = 5.6 µM).1,2,3 It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma with an IC50 value of 3 µM.1 It is also reported to compete with macrophage inflammatory protein-1α for binding to human CCR5 chemokine receptors with an IC50 value of 11 µM.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Machida, T.,Higashi, K. and Ogawara, H. Cochlioquinone A, an inhibitor of diacylglycerol kinase. J.Antibiot.(Tokyo) 48(10), 1076-1080 (1995).
2.Lee, H.B.,Lim, C.H.,Kwon, H.J., et al. Inhibitory activity of diacylglycerol acyltransferase by cochlioquinones A and A1. J.Antibiot.(Tokyo) 56(11), 967-969 (2003).
3.Yoganathan, K.,Yang, L.K.,Rossant, C., et al. Cochlioquinones and epi-cochlioquinones: Antagonists of the human chemokine receptor CCR5 from Bipolaris brizae and Stachybotrys chartarum. J.Antibiot.(Tokyo) 57(1), 59-63 (2004).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% |
| 计算分子量 | 532.7 |
| 分子式 | C30H44O8 |
| CAS号 | 32450-25-2 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
