JJH260
货号：
19384-5mg 基本售价：
12474.0 元 规格：
5 mg
产品信息
概述| 货号 | 19384-5mg |
| 描述 | JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). It blocks the hydrolysis of 9-PAHSA (Item No. 17037) with an IC50 value of 0.57 µM.1 JJH260 also inhibits the novel FAHFA hydrolase androgen-dependent TFPI-regulating protein (ADTRP; IC50 = 8.5 µM), as well as the serine hydrolase ABHD6 and the lysophospholipases LYPLA1 and LYPLA2.1 JJH260 inhibits the FAHFA hydrolase activity of LNCaP and T cell lysates and intact cells.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Parsons, W.H.,Kolar, M.J.,Kamat, S.S., et al. AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs. Nature Chemical Biology 12(5), 367-372 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥90% |
| 计算分子量 | 568.1 |
| 分子式 | C29H34ClN5O5 |
| CAS号 | 1831135-30-8 |
| 稳定性 | ≥ 2 years |
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