Oligomycin C
货号：
19162-5mg 基本售价：
12390.0 元 规格：
5 mg
产品信息
概述| 货号 | 19162-5mg |
| 描述 | Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin C is a minor component of the oligomycin complex (Item No. 11341) that acts as an inhibitor of the mitochondrial F1FO-ATP synthase.1 Inhibition of the ATP synthase by oligomycins leads to cell death.2 |
| 别名 | 12-deoxy Oligomycin A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Hong, S., and Pedersen, P.L. ATP synthase and the actions of inhibitors utilized to study its roles in human health, disease, and other scientific areas. Microbiology and Molecular Biology Reviews 72(4), 590-641 (2008).
2.Marton, A.,Mihalik, R.,Bratincsak, A., et al. Apoptotic cell death induced by inhibitors of energy conservation--Bcl-2 inhibits apoptosis downstream of a fall of ATP level. Eur. J. Biochem. 250(2), 467-475 (1997).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 775.1 |
| 分子式 | C45H74O10 |
| CAS号 | 11052-72-5 |
| 稳定性 | ≥ 2 years |
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