galacto-Dapagliflozin
货号：
15952-50mg 基本售价：
12320.0 元 规格：
50 mg
产品信息
概述| 货号 | 15952-50mg |
| 描述 | Renal glucose transport is mediated by sodium-glucose cotransporters (SGLT) 1 and 2.1 In humans, SGLT2 is responsible for the majority of glucose reabsorption in the kidney.1 galacto-Dapagliflozin is a potent inhibitor of human SGLT2 that is 1,000-fold less potent at human SGLT1 (Ki values are 2 and 25,000 nM, respectively).2 It also dissociates from hSGLT2 more slowly than from hSGLT1 (half-time off rates are 19 and 0.9 seconds, respectively).2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Hummel, C.S.,Lu, C.,Loo, D.D.F., et al. Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2. American Journal of Physiology.Cell Physiology 300, C14-C21 (2011).
2.Hummel, C.S.,Lu, C.,Liu, J., et al. Structural selectivity of human SGLT inhibitors. American Journal of Physiology.Cell Physiology 302(2), C373-C382 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 408.9 |
| 分子式 | C21H25ClO6 |
| CAS号 | 1408245-02-2 |
| 稳定性 | ≥ 2 years |
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