TC-E 5002 (50 MG)
货号:
5089/50 基本售价:
12274.1 元 规格:
50 mg
产品信息
概述货号 | 5089/50 |
别名 | N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine |
性能供应商 | Tocris |
生物活性 | Selective histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.2, 1.2, 6.8, 55, 83, >100 and >120 μM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A respectively). Inhibits growth of HeLa and KYSE-150 cancer cells in vitro. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 285.38 |
分子式 | C15H27NO4 |
可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO |
参考文献 | Suzukiet al (2013) Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity. J.Med.Chem. 56 (7222). PMID: 23964788. |