Sonepiprazole (50 MG)
货号：
4185/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 4185/50 |
| 别名 | 4-[4-[2-[(1S)-3,4-Dihydro-1H-2-benzopyran-1-yl)ethyl]-1-piperazinyl]-benzenesulfonamide |
性能| 供应商 | Tocris |
| 生物活性 | Selective, high affinity antagonist for the rat and human dopamine D4 receptor (Ki = 10 nM). Exhibits low affinity at other monoamine receptors (Ki > 2000 nM). Induces c-fos gene expression in medial prefrontal cortex in a similar manner to clozapine (Cat. No. 0444). Brain penetrant and orally available. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 401.52 |
| 分子式 | C21H27N3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Merchantet al (1996) Pharmacological characterization of U-101387, a dopamine D4 receptor selective antagonist. J.Pharm.Exp.Ther. 2791392. |
