| 货号 | 1250/50 |
| 别名 | (S)-α-Amino-2'-chloro-5-(phosphonomet |
| 供应商 | Tocris |
| 生物活性 | Competitive NMDA receptor antagonist (pKi = 7.7). Centrally active following oral administration (ED50 < 3.2 mg/kg for protection against MES-induced seizures). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 369.74 |
| 分子式 | C16H17ClNO5P |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO with gentle warming and to 100 mM in 1.1eq. NaOH |
| CAS号 | 174575-17-8 |
| 参考文献 | Bakshiet al (1999) Disruption of prepulse inhibition and increases in locomotor activity by competitive N-methyl-D-aspartate receptor antagonists in rats. J.Pharmacol.Exp.Ther. 288 643. PMID: 9918570. Urwyleret al (1996) Biphenyl-derivatives of 2-amino-7-phosphono-heptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonists - I. Pharmacological characterization in vitro. Neuropharmacology 35 643. PMID: 8887974. Urwyleret al (1996) Biphenyl-derivatives of 2-amino-7-phosphono-heptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonists - II. Pharmacological characterization in vivo. Neuropharmacology 35 655. PMID: 8887975. |