货号 | 3690/50 |
别名 | [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzo |
供应商 | Tocris |
生物活性 | Selective PPARγ agonist (EC50 = 8.83 nM). Drives normal adipocyte differentiation and exhibits a lipid-lowering effect; reduces atherosclerosis in E2-KI mice. Displays antidiabetic properties and improves hepatic insulin sensitivity in intralipid-infusion (IL) rats. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 519.57 |
分子式 | C28H25NO7S |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 353280-43-0 |
参考文献 | Sohnet al (2009) S26948, a new specific peroxisome proliferator activated receptor gamma modulator improved in vivo hepatic insulin sensitivity in 48 h lipid infused rats. Eur.J.Pharmacol. 608 104. PMID: 19250932. Carmonaet al (2007) S 26948: a new specific peroxisome proliferator-activated receptor γ modulator with potent antidiabetes and antiatherogenic effects. Diabetes 56 2797. PMID: 17704298. |