| 货号 | 1671/50 |
| 别名 | 3,6a,11,14-Tetrahydro-9-methoxy-2-m |
| 供应商 | Tocris |
| 生物活性 | Selective M4 muscarinic receptor antagonist. IC50 values are 91, 6559, 3441, 950 and 7412 nM for human M4, M1, M2, M3, and M5 receptors respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 392.45 |
| 分子式 | C23H24N2O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 23062-91-1 |
| 参考文献 | Bohmeet al (2002) Synthesis and pharmacology of benzoxazines as highly selective antagonists at M4 muscarinic receptors. J.Med.Chem. 45 3094. PMID: 12086495. Kitaichiet al (1999) A novel muscarinic M4 receptor antagonist provides further evidence of an autoreceptor role for the muscarinic M2 receptor sub-type. Eur.J.Pharmacol. 383 53. PMID: 10556681. Augelli-Szafranet al (1998) Identification and characterization of m4 selective muscarinic antagonists. Bioorg.Med.Chem.Lett. 8 1991. PMID: 9873472. |