| 货号 | 2450/50 |
| 别名 | 8,8'-[Carbonylbis[imino-3,1-phenylen |
| 供应商 | Tocris |
| 生物活性 | Purinergic receptor antagonist that potently inhibits P2Y11 receptor activity (IC50 = 463 nM). Displays selectivity for P2Y11 and P2X1 receptors over P2Y1, P2Y2 , P2X2, P2X3, P2X4 and P2X7 receptors. Inhibits NAD+-induced activation of human granulocytes. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 1437.08 |
| 分子式 | C49H28F2N6Na6O23S6 |
| 可溶性/溶解性 | Soluble to 50 mM in water |
| CAS号 | 104869-26-3 |
| 参考文献 | Moreschiet al (2006) Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes. J.Biol.Chem. 281 31419. PMID: 16926152. Ullmannet al (2005) Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency. J.Med.Chem. 48 7040. PMID: 16250663. |