货号 | 0373/50 |
别名 | 2,3-Dioxo-6-nitro-1,2,3,4-tetrahydr |
供应商 | Tocris |
生物活性 | Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo. NBQX disodium salt (Cat. No. 1044) also available. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 336.28 |
分子式 | C12H8N4O6S |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 118876-58-7 |
参考文献 | Nambaet al (1994) Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy. Brain Res. 638 36. PMID: 8199874. Sheardownet al (1993) The pharmacology of AMPA receptors and their antagonists. Stroke 24 146. PMID: 7504337. Gillet al (1992) The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline (NBQX) in a rat focal ischaemia model. Brain Res. 580 35. PMID: 1504814. Zeman and Lodge (1992) Pharmacological characterization of non-NMDA subtypes of glutamate receptors in the neonatal rat hemisected spinal cord in vitro. Br.J.Pharmacol. 106 367. PMID: 1382781. |