| 货号 | 4603/50 |
| 别名 | 2-Amino-4-(4-hydroxyphenyl)-6-[(1H- |
| 供应商 | Tocris |
| 生物活性 | Potent A2A and A2B adenosine receptor partial agonist ( Ki = 2.6 nM and EC50 = 12 nM respectively). Also exhibits selectivity for A1 over A3(Ki values are 2.6 and 538 nM respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 348.38 |
| 分子式 | C17H12N6OS |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Laneet al (2012) A novel nonribose agonist, LUF5834, engages residues that are distinct from those of adenosine-like ligands to activate the adenosine A2a receptor Mol.Pharmacol. 81 (3) 475. PMID: 22188926. Beukerset al (2004) New, non-adenosine, high potency agonists for the human adenosine A2B receptor with an improved selectivity profile compared to the reference agonist N-ethylcarboxamidoadenosine J.Med.Chem 47 (15) 3707. PMID: 15239649. |