Golgicide A (50 MG)
货号:
3584/50 基本售价:
12274.1 元 规格:
50 mg
产品信息
概述货号 | 3584/50 |
别名 | 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline |
性能供应商 | Tocris |
生物活性 | Potent, specific and reversible inhibitor of Golgi BFA resistance factor 1 (GBF1), an ArfGEF, that decreases Arf1 activation in vivo. Arrests secretion of soluble and membrane-associated proteins at the endoplasmic reticulum-Golgi intermediate compartment. Causes disassembly and dispersal of the Golgi and trans-Golgi network. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 284.3 |
分子式 | C17H14F2N2 |
可溶性/溶解性 | Soluble to 50 mM in DMSO |
CAS号 | 1139889-93-2 |
参考文献 | Saenzet al (2008) Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nature Chem.Biol. 5157. |