| 货号 | 3643/50 |
| 别名 | 2-[3-(4-Chlorophenyl)-2-[(2,4-dichl |
| 供应商 | Tocris |
| 生物活性 | Protease-activated receptor 1 (PAR1) antagonist. Exhibits potent antiplatelet activity in vitro; inhibits thrombin TRAP-6-induced platelet aggregation (IC50 = 2.5 μM) with no effect on coagulation time. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 469.73 |
| 分子式 | C19H11Cl3N2O4S |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| CAS号 | 173904-50-2 |
| 参考文献 | Katoet al (2003) Inhibition of arterial thrombosis by a protease-activated receptor 1 antagonist, FR171113, in the guinea pig. Eur.J.Pharmacol. 473 163. PMID: 12892834. Katoet al (1999) In vitro antiplatelet profile of FR171113, a novel non-peptide thrombin receptor antagonist. Eur.J.Pharmacol. 384 197. PMID: 10611442. |