CU CPT 4a (50 MG)
货号:
4883/50 基本售价:
12274.1 元 规格:
50 mg
产品信息
概述货号 | 4883/50 |
别名 | N-[(3-Chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine |
性能供应商 | Tocris |
生物活性 | Selective TLR3 inhibitor (IC50 = 3.44 μM in RAW 264.7 cells); suppresses downstream signaling pathways mediated by the TLR3/dsRNA complex, inhibiting TNF-α and IL-1β production in whole cells. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 377.82 |
分子式 | C18H13ClFNO3S |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in 1eq. NaOH |
参考文献 | Chenget al (2011) Small-molecule inhibitors of the TLR3/dsRNA complex. J.Am.Chem.Soc. 133 3764. PMID: 21355588. |