AZ 10417808 (50 MG)
货号：
2172/50 基本售价：
12274.1 元 规格：
50 mg
产品信息
概述| 货号 | 2172/50 |
| 别名 | 2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide; AQZ-1 |
性能| 供应商 | Tocris |
| 生物活性 | Selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 μM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC50 = 14.9 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 434.23 |
| 分子式 | C18H13C12N5O4 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| CAS号 | 331645-84-2 |
| 参考文献 | Scottet al (2003) Novel small molecule inhibitors of caspase-3 block cellular and biochemical features of apoptosis. J.Pharmacol.Exp.Ther. 304 433. PMID: 12490620. |
