AdipoRon hydrochloride (50 MG)
货号:
5096/50 基本售价:
12274.1 元 规格:
50 mg
产品信息
概述货号 | 5096/50 |
别名 | 2-(4-Benzyoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide hydrochloride |
性能供应商 | Tocris |
生物活性 | Agonist of adiponectin receptors AdipoR1 and AdipoR2 (Kd values are 1.8 and 3.1 μM respectively). Activates AMPK and PPARα signaling; ameliorates insulin resistance, dyslipidemia and glucose intolerance in db/db mice. Orally active antidiabetic agent. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 464.98 |
分子式 | C27H28N2O3 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
参考文献 | Okada-Iwabuet al (2013) A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature 503 493. PMID: 24172895. |