| 货号 | 3549/50 |
| 别名 | (1R,5S)-9-Bromo-1,2,3,4,5,6-hexahyd |
| 供应商 | Tocris |
| 生物活性 | Potent agonist of α4β4,α4β2 and α7 nACh receptors (IC50 values are 0.28, 0.30 and 31.6 nM respectively). Displays different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs (EC50 values are 0.008 and 0.05 μM respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 269.14 |
| 分子式 | C11H13BrN2O |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Moroniet al (2006) α4β2 nicotinic receptors with high and low acetylcholine sensitivity: pharmacology, stoichiometry, and sensitivity to long-term exposure to nicotine. Mol.Pharmacol. 70 755. PMID: 16720757. Houlihanet al (2001) Activity of cytisine and its brominated isoteres on recombinant human α7, α4β2 and α4β4 nicotinic acetylcholine receptors. J.Neurochem. 78 1029. PMID: 11553677. |