| 货号 | 9001534-50mg |
| 描述 | Agmatine is a natural polyamine formed by the enzymatic decarboxylation of arginine.1 It can be converted to putrescine by agmatinase or to guanidinobutyric acid by diamine oxidase and aldehyde dehydrogenase. Agmatine has numerous modulatory actions, particularly in pathways related to diabetes, immunity, and neurophysiology.1 N-Acetylagmatine is a potential monoacetylated derivative of agmatine. The enzyme-mediated acetylation of polyamines is commonly considered a degradative step, with monoacetylated polyamines detected in the urine.1,2,3 However, monoacetylated polyamines can stimulate diamine oxidase activity, suggesting that N-acetylagmatine might have physiologically important actions.4 |
| 别名 | Monoacetylagmatine; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Piletz, J.E.,Aricioglu, F.,Cheng, J.T., et al. Agmatine: clinical applications after 100 years in translation. Drug Discovery Today 18(17-18), 880-893 (2013). 2.van den Berg, G.A.,Muskiet, F.A.,Kingma, A.W., et al. Simultaneous gas-chromatographic determination of free and acetyl-conjugated polyamines in urine. Clinical Chemistry 32(10), 1930-1937 (1986). 3.Seiler, N., and Al-Therib, M.J. Putrescine catabolism in mammalian brain. Biochemistry Journal 144(1), 29-35 (1974). 4.Perin, A.,Sessa, A., and Desiderio, M.A. Response of tissue diamine oxidase activity to polyamine administration. Biochemistry Journal 234(1), 119-123 (1986). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 232.3 |
| 分子式 | C7H16N4O • C2H4O2 |
| 稳定性 | ≥ 2 years |
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