Illudin M
货号：
22062-5mg 基本售价：
12250.0 元 规格：
5 mg
产品信息
概述| 货号 | 22062-5mg |
| 描述 | Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA.1 It is cytotoxic to HL-60 human leukemia cells at 6-100 nM.2 Illudin M was used as a base structure for the development of potential anticancer agents with less toxicity and improved efficacy.3,1 It is closely related to illudin S (Item No. 17451), which has been the focus of additional studies. |
| 别名 | DR-15977;(-)-Illudin M;NSC 400978;NSC 626370; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Jacobson, J.M.,Feinman, L.,Liebes, L., et al. Pharmacokinetics, safety, and antiviral effects of hypericin, a derivative of St. John’s wort plant, in patients with chronic hepatitis C virus infection. Antimicrob. Agents and Chemother. 45(2), 517-524 (2001).
2.Kelner, M.J.,McMorris, T.C.,Beck, W.T., et al. Preclinical evaluation of illudins as anticancer agents. Cancer Research 47(12), 3186-3189 (1987).
3.Schobert, R.,Knauer, S.,Seibt, S., et al. Anticancer active illudins: Recent developments of a potent alkylating compound class. Current Medicinal Chemistry 18, 790-807 (2011).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 248.3 |
| 分子式 | C15H20O3 |
| CAS号 | 1146-04-9 |
| 稳定性 | ≥ 2 years |
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