| 货号 | 17454-5mg |
| 描述 | Nemadectin is a macrocyclic lactone antibiotic that demonstrates endectocidal and nematocidal activity.1 Differing only by the unsaturated side-chain extending from the 6,6-spiroketal core, this antibiotic is structurally similar to milbemycins and avermectins.2 Nemadectin has been used as starting material for the production of the veterinary anthelmintic, moxidectin, and its derivatives have been explored for their potential antiparasitic use.3,4 |
| 别名 | CL-287088;LL-F28249 α; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Doscher, M.E.,Wood, I.B.,Pankavich, J.A., et al. Efficacy of nemadectin, a new broad-spectrum endectocide, against natural infections of canine gastrointestinal helminths. Veterinary Parasitology 34(3), 255-259 (1989). 2.Carter, G.T.,Nietsche, J.A.,Hertz, M.R., et al. LL-F28249 antibiotic complex: A new family of antiparasitic macrocyclic lactones. Isolation, characterization and structures of LL-F28249 α, β, γ, λ. J.Antibiot.(Tokyo) 41(4), 519-529 (1988). 3.Fang, K.,Schlingmann, G.,Enos, A., et al. New biotransformation products of nemadectins. J.Antibiot.(Tokyo) 54(10), 805-809 (2001). 4.Yang, L.Y.,Wang, J.D.,Zhang, J., et al. New nemadectin congeners with acaricidal and nematocidal activity from Streptomyces microflavus neau3 Y-3. Bioorganic & Medicinal Chemistry Letters 23(20), 5710-5713 (2013). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 612.8 |
| 分子式 | C36H52O8 |
| CAS号 | 102130-84-7 |
| 稳定性 | ≥ 2 years |
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