Nimbolide
货号：
19230-25mg 基本售价：
12194.0 元 规格：
25 mg
产品信息
概述| 货号 | 19230-25mg |
| 描述 | Nimbolide is a terpenoid lactone first isolated from A. indica (Neem tree) that demonstrates antimalarial and anticancer effects in experimental models.1 It inhibits pancreatic cancer cell growth and metastasis by inducing the excessive generation of reactive oxygen species, reducing PI3K/Akt/mTOR and ERK signaling, and up-regulating the pro-apoptotic proteins Bax, caspase-3, and PARP.1 |
| 别名 | NSC 309909; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Subramani, R.,Gonzalez, E.,Arumugam, A., et al. Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition. Sci.Rep. 6:19819, (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 466.5 |
| 分子式 | C27H30O7 |
| CAS号 | 25990-37-8 |
| 稳定性 | ≥ 1 year |
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