Apoptolidin
货号：
19435-500ug 基本售价：
12040.0 元 规格：
500 ug
产品信息
概述| 货号 | 19435-500ug |
| 描述 | Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsisbacteria.1 It inhibits the mitochondrial F1FO ATPase (Ki = 4-5 µM).2,3 Apoptolidin selectively kills transformed glial cells without significantly affecting untransformed cells.3 It also has antibiotic and antifungal actions.1,3 |
| 别名 | Apoptolidin A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kim, J.W.,Adachi, H.,Shin-Ya, K., et al. Apoptolidin, a new apoptosis inducer in transformed cells from Nocardiopsis sp. J.Antibiot.(Tokyo) 50(7), 628-630 (1997).
2.Salomon, A.R.,Voehringer, D.W.,Herzenberg, L.A., et al. Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of F0F1-ATPase. Proceedings of the National Academy of Sciences of the United States of America 97(26), 14766-14771 (2000).
3.Salomon, A.R.,Voehringer, D.W.,Herzenberg, L.A., et al. Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase. Chemistry & Biology 8, 71-80 (2001).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1129.4 |
| 分子式 | C58H96O21 |
| CAS号 | 194874-06-1 |
| 稳定性 | ≥ 2 years |
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