| 货号 | 19269-25mg |
| 描述 | Pheleuin is a pyrazinone derivative synthesized from a dipeptide aldehyde.1,2 Although the biological activity of this compound has not been reported, similar diketopiperazines are known to inhibit calpain and/or regulate S. aureus virulence factor expression.3,4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Taguchi, H.,Yokoi, T. and Okada, Y. Facile synthesis of 2(1H)-pyrazinone derivatives from dipeptides. Peptide Chemistry 32, 169-172 (1994). 2.Wilson, D.J.,Shi, C.,Teitelbaum, A.M., et al. Characterization of AusA: A dimodular nonribosomal peptide synthetase responsible for the production of aureusimine pyrazinones. Biochem. 52(5), 926-937 (2013). 3.Zeng, Y.,Li, Q.,Hanzlik, R.P., et al. Synthesis of a small library of diketopiperazines as potential inhibitors of calpain. Bioorganic & Medicinal Chemistry Letters 15(12), 3034-3038 (2005). 4.Zimmermann, M. and Fischbach, M.A. A family of pyrazinone natural products from a conserved nonribosomal peptide synthetase in Staphylococcus aureus. Chemistry & Biology 17(9), 925-930 (2010). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 242.3 |
| 分子式 | C15H18N2O |
| CAS号 | 169195-23-7 |
| 稳定性 | ≥ 2 years |
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