TAK 21d (50 MG)
货号:
5209/50 基本售价:
11976.7 元 规格:
50 mg
产品信息
概述货号 | 5209/50 |
别名 | 4-[4-(3,4-Difluorophenyl)-2-pyrimidinyl]-N-3-pyridazinyl-1-piperazinecarboxamide |
性能供应商 | Tocris |
生物活性 | Potent FAAH inhibitor; (IC50 values are 0.28 and 0.72 nM, at rat and human FAAH respectively). Displays analgesic effects in vivo models of neuropathic and inflammatory pain. Brain penetrant. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 397.38 |
分子式 | C19H17F2N7 |
可溶性/溶解性 | Soluble to 10 mM in DMSO and to 20 mM in 1eq. HCl |
参考文献 | Konoet al (2014) Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors. Bioorg.Med.Chem. 22 1468. PMID: 24440478. |