SR 7826 (50 MG)
货号：
5626/50 基本售价：
11976.7 元 规格：
50 mg
产品信息
概述| 货号 | 5626/50 |
| 别名 | N-(2-Hydroxyethyl)-N'-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective LIMK inhibitor (IC50 values are 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). Inhibits cofilin phosphorylation in A7r5 cells and suppresses migration and invasion of PC-3 cells in vitro. Orally bioavailable. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 387.43 |
| 分子式 | C22H21N5O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Yinet al (2015) Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors. J.Med.Chem. 58 1846. PMID: 25621531. |
