| 货号 | 2913/50 |
| 别名 | (Z)-1-[2-Cycloheptyloxy-2-(2,6-dich |
| 供应商 | Tocris |
| 生物活性 | Selective, non-competitive mGlu2 antagonist. Inhibits GTPγ35S binding to mGlu2-containing membranes (IC50 = 0.11 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 352.26 |
| 分子式 | C17H19Cl2N3O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Brauner-Osbourneet al (2007) Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors. Curr.Drug Targets. 8 169. PMID: 17266540. Kolczewskiet al (1999) Synthesis of heterocyclic enol ethers and their use as a group 2 metabotropic glutamate receptor antagonists. Bioorg.Med.Chem.Lett. 9 2173. PMID: 10465539. |