RN 1 dihydrochloride (50 MG)
货号：
4977/50 基本售价：
11976.7 元 规格：
50 mg
产品信息
概述| 货号 | 4977/50 |
| 别名 | 1-(4-methyl-1-piperazinyl)-2-[[(1R*,2S*)-2-[4-phenylmethoxy)phenyl]cyclopropyl]amino]ethanone dihydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Potent lysine specific demethylase 1 (LSD1) inhibitor (IC50 = 70 nM). Exhibits selectivity for LSD1 over MAO-A and MAO-B (IC50 values are 0.51 and 2.79 μM for MAO-A and MAO-B, respectively). Impairs long-term, but not short-term memory in mice. Brain penetrant following systemic administration. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 452.42 |
| 分子式 | C23H29N3O2 |
| 可溶性/溶解性 | Soluble to 20 mM in water and to 20 mM in DMSO with gentle warming |
| 参考文献 | Neelamegamet al (2012) Brain-penetrant LSD1 inhibitors can block memory consolidation. ACS Chem.Neurosci. 3 120. PMID: 22754608. |
