OXA 06 dihydrochloride (50 MG)
货号：
5182/50 基本售价：
11976.7 元 规格：
50 mg
产品信息
概述| 货号 | 5182/50 |
| 别名 | 2-Fluoro-N-[[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methyl]benzenemethanamine dihydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Potent ROCK inhibitor (IC50 = 10 nM). Suppresses pMYPT1 and pCofilin levels in non-small cell lung carcinoma (NSCLC) cell lines. Also inhibits anchorage-independent growth of NSCLC cell lines in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 404.31 |
| 分子式 | C21H18FN3.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Vigilet al (2012) ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion. Cancer Res. 72 5338. PMID: 22942252. |
