NSC 636819 (50 MG)
货号:
5287/50 基本售价:
11976.7 元 规格:
50 mg
产品信息
概述货号 | 5287/50 |
别名 | 1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene |
性能供应商 | Tocris |
生物活性 | KDM4A/KDM4B inhibitor; inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro. Also negatively regulates androgen-responsive genes. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 510.15 |
分子式 | C22H12Cl4N2< |
可溶性/溶解性 | Soluble to 10 mM in DMSO |
参考文献 | Chuet al (2014) KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor. J.Med.Chem. 57 5975. PMID: 24971742. |