NGD 98-2 hydrochloride (50 MG)
货号：
4315/50 基本售价：
11976.7 元 规格：
50 mg
产品信息
概述| 货号 | 4315/50 |
| 别名 | N-(1-Ethylpropyl)-3-methoxy-5-[2-methoxy-4-(trifluoromethoxy)phenyl]-6-methyl-2-pyrazinamine hydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | High affinity antagonist of corticotropin-releasing factor receptor 1 (CRF1) (Ki = 1 nM). Orally available and brain penetrant. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 435.87 |
| 分子式 | C19H24F3N3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 5 mM in water with gentle warming |
| 参考文献 | Hodgettset al (2011) Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist. J.Med.Chem. 54 4187. PMID: 21618986. |
