N106 (50 MG)
货号:
5681/50 基本售价:
11976.7 元 规格:
50 mg
产品信息
概述货号 | 5681/50 |
别名 | 4-Methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl-2-benzothiazolamine |
性能供应商 | Tocris |
生物活性 | Activator of SUMO-activating enzyme, E1 ligase. Increases SERCA2a SUMOylation and activity, and enhances contractility in rat cardiomyocytes in vitro. Improves ventricular function in a mouse model of heart disease. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 354.38 |
分子式 | C17H14N4O3 |
可溶性/溶解性 | Soluble to 20 mM in DMSO |
参考文献 | Khoet al (2015) Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nat.Commun. 6 7229. PMID: 26068603. |