MJ 15 (50 MG)
货号：
4063/50 基本售价：
11976.7 元 规格：
50 mg
产品信息
概述| 货号 | 4063/50 |
| 别名 | 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(3-pyridinylmethyl)-1H-pyrazole-3-carboxamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective CB1 receptor antagonist (Ki = 27.2 pM, IC50 = 118.9 pM for rat CB1 receptors). Exhibits potency in obesity and hyperlipidemia models; inhibits food intake and increases in body weight in diet-induced obese rats and mice. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 471.77 |
| 分子式 | C23H17Cl3N4< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Chenet al (2010) Novel, selective antagonist of the cannabinoid CB1 receptor, MJ15, with prominent anti-obesity effect in rodent models. Eur.J.Pharmacol. 637 178. PMID: 20380831. |
