LTURM 34 ( )
货号：
5834/50 基本售价：
11828.0 元 规格：
50 mg
产品信息
概述| 货号 | 5834/50 |
| 别名 | 8-(4-Dibenzothienyll)-2-(4-morpholinyl)-4H-1,3-benzoxazin-4-one |
性能| 供应商 | Tocris |
| 生物活性 | Potent DNA-PK inhibitor (IC50 = 34 nM). Exhibits 170-fold selectivity for DNA-PK over PI3-K. Attenuates proliferation of a wide range of tumor cell lines in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 414.48 |
| 分子式 | C24H18N2O3 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| 参考文献 | Morrisonet al (2016) Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur.J.Med.Chem. 110 326. PMID: 26854431. |
