| 货号 | 20799-100mg |
| 描述 | Piperaquine is a bisquinoline compound that is often used in combination with artimesinin for inhibition of HIV-1 replication.1,2,3 It inhibits the ex vivo growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM.4 |
| 别名 | Piperaquinoline; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Askling, H.H.,Bruneel, F.,Burchard, G., et al. Management of imported malaria in Europe. Malar.J. 11, 1-15 (2012). 2.Henrich, P.P.,OBrien, C.,Sáenz, F.E., et al. Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model. Antimicrobial Agents and Chemotherapy 58(1), 183-195 (2014). 3.Pascual, A.,Parola, P.,Benoit-Vical, F., et al. Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparum. Malar.J. 11, 1-9 (2012). 4.Akoachere, M.,Buchholz, K.,Fischer, E., et al. In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins. Antimicrobial Agents and Chemotherapy 49(11), 4592-4597 (2005). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 535.5 |
| 分子式 | C29H32Cl2N6 |
| CAS号 | 4085-31-8 |
| 稳定性 | ≥ 2 years |
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