货号 | 4447/50 |
别名 | N-Methyl-N-[(3R)-3-phenyl-3-[4-(tri |
供应商 | Tocris |
生物活性 | Inhibitor of the glial glycine transporter (GlyT1); derivative of Org 24598 (Cat. No. 4035). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 367.36 |
分子式 | C19H20F3NO3< |
可溶性/溶解性 | Soluble to 10 mM in water with gentle warming and to 100 mM in DMSO |
参考文献 | Chueet al (2013) Glycine reuptake inhibition as a new therapeutic approach in schizophrenia: focus on the glycine transporter 1 (GlyT1). Curr.Pharm.Des. 19 1311. PMID: 23194655. Brownet al (2001) Discovery and SAR of org 24598-a selective glycine uptake inhibitor. Bioorg.Med.Chem.Lett. 11 2007. PMID: 11454468. |