5-chloro-5-Deoxyadenosine (hydrate)
货号：
21012-5g 基本售价：
11550.0 元 规格：
5 g
产品信息
概述| 货号 | 21012-5g |
| 描述 | 5-chloro-5-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5’-adenosyl)-L-methionine (SAM; Item No. 13956) can be converted to 5’-chloro-5’-deoxyadenosine in a reaction catalyzed by a SAM-dependent chlorinase.1 Through a 7-step route, 5-chloro-5-deoxyadenosine can be converted to chloroethylmalonyl-CoA, which has been shown to be involved in the biosynthesis of the anticancer agent salinosporamide A (Item No. 10007311) in the marine bacterium S. tropica.1 |
| 别名 | 5’-ClDA;5-Deoxy-5-chloroadenosine; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Eustáquio, A.S.,McGlinchey, R.P.,Liu, Y., et al. Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine. Proc. Natl. Acad. Sci. USA 106(30), 12295-12300 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 285.7 |
| 分子式 | C10H12ClN5O3 • XH2O |
| CAS号 | 698999-09-6 |
| 稳定性 | ≥ 2 years |
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