BMS 195614
货号：
16029-50mg 基本售价：
11382.0 元 规格：
50 mg
产品信息
概述| 货号 | 16029-50mg |
| 描述 | BMS 195614 is a neutral retinoic acid receptor (RAR) α-selective antagonist (Ki = 2.5 nM).1 It antagonizes agonist-induced coactivator recruitment and moderately decreases SMRT binding to RAR but does not significantly affect nuclear receptor corepressor binding.2 |
| 别名 | BMS 614; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Géhin, M.,Vivat, V.,Wurtz, J.M., et al. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chemistry & Biology 6(8), 519-529 (1999).
2.Germain, P.,Gaudon, C.,Pogenberg, V., et al. Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists. Chemistry & Biology 16(5), 479-489 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 448.5 |
| 分子式 | C29H24N2O3 |
| CAS号 | 182135-66-6 |
| 稳定性 | ≥ 2 years |
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