(-)-Warfarin
货号:
13531-25mg 基本售价:
11382.0 元 规格:
25 mg
产品信息
概述货号 | 13531-25mg |
描述 | Warfarin is an anti-coagulant used to prevent heart attacks, strokes and the formation of blood clots. It interferes with the use of vitamin K in the required carboxylation of several vitamin K-dependent proteins in the clotting cascade, preventing the initiating of clotting.1 (±)-Warfarin is a racemic mixture of two optically active isomers. (−)-Warfarin differs from (+)-warfarin by being five times more potent as a vitamin K antagonist.1 However, the two isomers are metabolized in vivo by different pathways, and (−)-warfarin has a shorter terminal elimination half-life (24-33 hours) than (+)-warfarin (35-58 hours).2 |
别名 | (S)-Warfarin; |
性能供应商 | Cayman |
应用文献 |
1.Hirsh, J.,Fuster, V.,Ansell, J., et al. American heart association/american college of cardiology foundation guide to warfarin therapy. J. Am. Coll. Cardiol. 41(9), 1633-1652 (2003). 2.Ufer, M. Comparative pharmacokinetics of vitamin K antagonists warfarin, phenprocoumon and acenocoumarol. Clinical Pharmacokinetics 44(12), 1227-1246 (2005).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 308.3 |
分子式 | C19H16O4 |
CAS号 | 5543-57-7 |
稳定性 | ≥ 2 years |
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