JZP 430 ( )
货号:
5844/50 基本售价:
11381.8 元 规格:
50 mg
产品信息
概述货号 | 5844/50 |
别名 | 4-(4-Morpholinyl)-1,2,5-thiadiazol-3-ylN-cyclooctyl-N-methylcarbamate |
性能供应商 | Tocris |
生物活性 | Potent and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor (IC50 = 44 nM). Exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 354.47 |
分子式 | C16H26N4O3 |
可溶性/溶解性 | Soluble to 50 mM in DMSO and to 20 mM in ethanol |
参考文献 | Patelet al (2015) Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. Chem.Med.Chem. 10 253. PMID: 25504894. |