YE 120 (50 MG)
货号:
4457/50 基本售价:
11381.8 元 规格:
50 mg
产品信息
概述货号 | 4457/50 |
别名 | 2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile |
性能供应商 | Tocris |
生物活性 | GPR35 agonist (EC50 = 32 nM in DMR assays). Also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM). |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 330.17 |
分子式 | C16H9Cl2N3 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Denget al (2011) Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J.Med.Chem. 54 7385. PMID: 21950657. |