| 货号 | 1057/50 |
| 别名 | (S)-4-[2-[Bis(cyclohexylamino)methy |
| 供应商 | Tocris |
| 生物活性 | The first potent, non-peptide, competitive bradykinin B2 receptor antagonist. In organ bath studies, WIN 64338 inhibits [3H]-bradykinin binding on guinea pig trachea with nanomolar affinity but is not active in the rabbit aorta (the classical bradykinin B1preparation). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 计算分子量 | 783.95 |
| 分子式 | C45H68ClN4OP.HCl |
| 可溶性/溶解性 | Soluble to 75 mM in DMSO |
| CAS号 | 151039-63-3 |
| 参考文献 | Huet al (2004) Action of bradykinin in the submucosal plexus of guinea pig small intestine. J.Pharmacol.Exp.Ther. 309 320. PMID: 14718600. Scherreret al (1995) Effects of WIN 64338, a nonpeptide bradykinin B2 receptor antagonist, on guinea-pig trachea. Br.J.Pharmacol. 115 1127. PMID: 7582533. Marceauet al (1994) Effects of peptide and nonpeptide antagonists of bradykinin B2 receptors on the venoconstrictor action of bradykinin. J.Pharmacol.Exp.Ther. 269 1136. PMID: 8014858. |