| 货号 | 3736/50 |
| 别名 | 5-(2-Oxo-2-phenylethoxy)-3,4-dihydr |
| 供应商 | Tocris |
| 生物活性 | Selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC50 values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 279.29 |
| 分子式 | C17H13NO3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 1048371-03-4 |
| 参考文献 | Moroniet al (2009) Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. Br.J.Pharmacol. 157 854. PMID: 19422384. Pellicciariet al (2008) On the way to selective PARP-2 inhibitors. Design, synthesis and preliminary evaluation of a series of isoquinolinone derivatives. Chem.Med.Chem 3914. |