货号 | 3688/50 |
别名 | 1-Methyl-3-(1-methyl-4-piperindin-4 |
供应商 | Tocris |
生物活性 | Selective antagonist of the 5-HT6 subtype of the serotonin receptor. Useful for the treatment of cognitive impairment that is associated with schizophrenia and Alzheimer's disease. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 510.51 |
分子式 | C21H22F2N2 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Kimet al (2008) New serotonin 5-HT6 ligands from common feature pharmacophore hypotheses. J.Chem.Inf.Model. 48 197. PMID: 18044950. Romeroet al (2006) Efficacy of selective 5-HT6 receptor ligands determined by monitoring 5-HT6 receptor-mediated cAMP signaling pathways. Br.J.Pharmocol. 148 1133. PMID: 16865095. |